Samba Shiva Reddy, Krishna Kripal*, Sushma Reddy Bhavanam, Prathush Ajith Kumar, Kavita Chandrasekaran, Aiswarya Dileep, Manjunath
Aim: Aim of the present study was clinical and radiographic evaluation and comparison of the efficacy of periodontal regeneration of intrabony defects using demineralized bone matrix (ColoCast®) alone and in conjunction with beta tri calcium phosphate (R.T.R®).
Materials and Methods: A total of 45 intrabony defects were treated in 28 patients. Defects were randomly divided by using lot technique into group I (n=15; ColoCast®), group II (n=15; ColoCast® + R.T.R®) and group III (n=15; OFD). Clinical parameters included of plaque index, gingival index, probing depth (PD), clinical attachment level (CAL), gingival recession (GR), and cemento enamel junction from a fixed reference point (acrylic stent). Radiographic parameters included radiographic defect depth, radiographic defect fill, percentage defect fill and radiographic bone density analysis. Radiographs were recorded and analyzed using radiovisiography (RVG) and film grid. All the parameters were recorded at baseline, 3, 6 and 9 months visits.
Results: The mean PD reduction, gain in CAL, mean GR, reduction in mean radiographic defect depth and mean percentage defect fill was 3.87mm, 2.87mm, 0.33mm, 2.73mm and 27.8% respectively in group I at 9 months. The mean probing depth reduction, gain in clinical attachment level, mean gingival recession, reduction in mean radiographic defect depth and mean percentage defect fill was 5.20mm, 4.60mm, 0.33mm, 4.33mm and 30.7% respectively in group II at 9 months. The mean PD reduction, gain in CAL, mean GR, reduction in mean radiographic defect depth and mean percentage defect fill was 2.93mm, 2.73mm, 0.47mm, 3.07mm and 26.3% respectively in group III at 9 months.
Conclusion: Within the limits of the present study, it can be concluded that regenerative periodontal surgery with both demineralized bone matrix (ColoCast)® alone and in conjunction with beta tri calcium phosphate (R.T.R)® resulted significant clinical improvements in intrabony defects when compared to open flap debridement alone, as evidenced by reduction in probing depths and gain in clinical attachment level and satisfactory defect fill. Improvement of clinical and radiographic parameters at sites treated with ColoCast® + R.T.R® were better compared to that of sites treated with ColoCast® alone and OFD.
