Formulation, Development and Evaluation of Rivaroxaban Tablets by Using Solubility Enhancement Technique

 

Piyush Patel*,  Ravi Patel,  Yogesh Patel

To enhance solubility and dissolution rate of Rivaroxaban by Inclusion complex with kneading method using Hydroxy propyl β cyclodextrin. The prepared Rivaroxaban inclusion complex were characterized in term of solubility and dissolution studies, Fourier transform infrared spectroscopy (FTIR). The aqueous solubility and dissolution rate of Rivaroxaban tablets was significantly increased. The dissolution rate of Rivaroxaban tablets was superior with compared to market sample.